How often do you need to replace air separator filters? Air separator filter usually last from 6 – 12 months depending on the air quality. Updated on September 10, 2020 Was this article helpful? Yes No Related Articles Diagnose Conference Error How often do air separator filters need to be replaced? LiveCare IOS camera setting for older iPhone and iPad Inaccuracy Report Pulse Oximeter Troubleshooting My unit gets hot and shuts down after 45 minutes?